Jonas Salk used this syringe during the testing of his polio vaccine. In the early tests carried out in 1952 and 1953, Salk gave all the vaccinations himself. The first subjects included children at the D. T. Watson Home for Crippled Children, residents of the Polk State Home, Salk, and members of his laboratory staff. In 1953, the first community-based, pilot vaccine trial was carried out with volunteer families in the Pittsburgh area. A second pilot trial included thousands of Pittsburgh schoolchildren. The success of these early tests paved the way for the Salk Vaccine National Field Trial of 1954.