Summary
The sequence of the nucleocapsid (N) protein of Machupo virus (causative agent of Bolivian haemorrhagic fever) has been determined, and used to infer a phylogenetic relationship to other arenaviruses. The relationship of the virus to Junín and Tacaribe viruses, together with previous demonstrations of antigenic similarity and cross-protection by heterologous viruses, suggest that vaccines developed against Argentine haemorrhagic fever might also be effective against the Bolivian disease.
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Griffiths, C.M., Wilson, S.M. & Clegg, J.C.S. Sequence of the nucleocapsid protein gene of Machupo virus: close relationship with another South American pathogenic arenavirus, Junín. Archives of Virology 124, 371–377 (1992). https://doi.org/10.1007/BF01309817
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DOI: https://doi.org/10.1007/BF01309817